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1

Identification of Potent and Selective Small-Molecule Inhibitors of Caspase-3 through the Use of Extended Tethering and Structure-Based Drug Design

DeLano, Warren L., Fahr, Bruce, Choong, Ingrid C., Lew, Willard, Lee, Dennis, Pham, Phuongly, Burdett, Matthew T., Lam, Joni W., Wiesmann, Christian, Luong, Tinh N.

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 651 KB

english, 2002

2

WhatÊ¼s New in Shock, April 2020?

Cirino, Jennifer A., Delano, Matthew J., Napolitano, Lena M.

Journal:

Year:

2020

Language:

english

File:

PDF, 208 KB

english, 2020

3

Immune checkpoint inhibition in sepsis: a Phase 1b randomized study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of nivolumab

Hotchkiss, Richard S., Colston, Elizabeth, Yende, Sachin, Crouser, Elliott D., Martin, Greg S., Albertson, Timothy, Bartz, Raquel R., Brakenridge, Scott C., Delano, Matthew J., Park, Pauline K., Donni

Journal:

Intensive Care Medicine

Year:

2019

Language:

english

File:

PDF, 810 KB

english, 2019

4

Identification of potent and novel small-Molecule inhibitors of caspase-3

Darin A Allen, Phuongly Pham, Ingrid C Choong, Bruce Fahr, Matthew T Burdett, Willard Lew, Warren L DeLano, Eric M Gordon, Joni W Lam, Tom O'Brien, Dennis Lee

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 246 KB

english, 2003

5

The immune system's role in sepsis progression, resolution, and long-term outcome

Delano, Matthew J., Ward, Peter A.

Journal:

Immunological Reviews

Year:

2016

Language:

english

File:

PDF, 776 KB

english, 2016

6

INCREASED MORTALITY AND ALTERED IMMUNITY IN NEONATAL SEPSIS PRODUCED BY GENERALIZED PERITONITIS

Wynn, James L., Scumpia, Philip O., Delano, Matthew J., O'Malley, Kerri A., Ungaro, Ricardo, Abouhamze, Amer, Moldawer, Lyle L.

Journal:

Year:

2007

Language:

english

File:

PDF, 817 KB

english, 2007

7

Emerging implications of nanotechnology on cancer diagnostics and therapeutics

Alex G. Cuenca, Huabei Jiang, Steven N. Hochwald, Matthew Delano, William G. Cance, Stephen R. Grobmyer

Journal:

Year:

2006

Language:

english

File:

PDF, 223 KB

english, 2006

8

[IEEE 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) - Orlando, FL, USA (2016.8.16-2016.8.20)] 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) - Noninvasive and continuous blood pressure measurement via superficial temporal artery tonometry

Canning, Julia, Helbert, Kendall, Iashin, Grigoriy, Matthews, Jonathan, Yang, Jason, Delano, Margaret K., Sodini, Charles G., Zhang, Quan

Year:

2016

Language:

english

File:

PDF, 803 KB

english, 2016

9

Electroporation-mediated delivery of FER gene enhances innate immune response and improves survival in a murine model of pneumonia

Dolgachev, Vladislav, Panicker, Sreehari, Balijepalli, Sanjay, McCandless, Lane Kelly, Yin, Yue, Swamy, Samantha, Suresh, M. V., Delano, Matthew J., Hemmila, Mark R., Raghavendran, Krishnan, Machado-A

Journal:

Year:

2018

Language:

english

File:

PDF, 4.34 MB

english, 2018

10

Traditional Resuscitative Practices Fail to Resolve Metabolic Acidosis in Morbidly Obese Patients After Severe Blunt Trauma

Winfield, Robert D., Delano, Matthew J., Lottenberg, Lawrence, Cendan, Juan C., Moldawer, Lyle L., Maier, Ronald V., Cuschieri, Joseph

Journal:

The Journal of Trauma Injury Infection and Critical Care

Year:

2010

Language:

english

File:

PDF, 1.54 MB

english, 2010

11

Sex differences in auditory brainstem response audiograms from vasopressin-deficient Brattleboro and wild-type Long-Evans rats

Charlton, Payton E., Schatz, Kelcie C., Burke, Kali, Paul, Matthew J., Dent, Micheal L., Delano, Paul Hinckley

Journal:

Year:

2019

Language:

english

File:

PDF, 782 KB

english, 2019

12

Differences in outcome between obese and nonobese patients following severe blunt trauma are not consistent with an early inflammatory genomic response

Winfield, Robert D., Delano, Matthew J., Dixon, David J., Schierding, William S., Cendan, Juan C., Lottenberg, Lawrence, Lopez, M Cecilia, Baker, Henry V., Cobb, J Perren, Moldawer, Lyle L., Maier, Ro

Journal:

Critical Care Medicine

Year:

2010

Language:

english

File:

PDF, 708 KB

english, 2010

13

Whatʼs New in Shock, December 2017?

Delano, Matthew J., Raghavendran, Krishnan

Journal:

Year:

2017

Language:

english

File:

PDF, 189 KB

english, 2017

14

Complications and resource utilization in trauma patients with diabetes

He, Katherine, Hemmila, Mark R., Cain-Nielsen, Anne H., Machado-Aranda, David A., Frydrych, Lynn M., Delano, Matthew J., Efron, Philip Alexander

Journal:

Year:

2019

Language:

english

File:

PDF, 428 KB

english, 2019

15

A comparison of the cyclooxygenase inhibitor-NO donors (CINOD), NMI-1182 and AZD3582, using in vitro biochemical and pharmacological methods

Delano V. Young, Edward D. Cochran, Vijay Dhawan, Richard A. Earl, James L. Ellis, David S. Garvey, David R. Janero, Subhash P. Khanapure, L. Gordon Letts, Terry L. Melim, Madhavi G. Murty, Matthew J.

Journal:

Biochemical Pharmacology

Year:

2005

Language:

english

File:

PDF, 464 KB

english, 2005

16

Non-compliance with ACS-COT recommended criteria for full trauma team activation is associated with undertriage deaths

Tignanelli, Christopher J., Vander Kolk, Wayne E., Mikhail, Judy N., Delano, Matthew J., Hemmila, Mark R.

Journal:

Journal of Trauma and Acute Care Surgery

Year:

2017

Language:

english

File:

PDF, 1.59 MB

english, 2017

17

Long-Term Incidence of Amputation in Diabetic and Non-Diabetic Patients with Osteomyelitis

Keeney-Bonthrone, Toby P., Hawes, Armani M., Frydrych, Lynn M., Delano, Matthew J.

Journal:

Journal of the American College of Surgeons

Year:

2018

Language:

english

File:

PDF, 92 KB

english, 2018

18

Synthesis and Structure−Activity Relationship of Novel, Highly Potent Metharyl and Methcycloalkyl Cyclooxygenase-2 (COX-2) Selective Inhibitors

Khanapure, Subhash P., Garvey, David S., Young, Delano V., Ezawa, Maiko, Earl, Richard A., Gaston, Rick D., Fang, Xinqin, Murty, Madhavi, Martino, Allison, Shumway, Matthew, Trocha, Mark, Marek, Przem

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 392 KB

english, 2003

19

Obese Patients Show a Depressed Cytokine Profile Following Severe Blunt Injury

Winfield, Robert D., Delano, Matthew J., Cuenca, Alex G., Cendan, Juan C., Lottenberg, Lawrence, Efron, Philip A., Maier, Ronald V., Remick, Daniel G., Moldawer, Lyle L., Cuschieri, Joseph

Journal:

Year:

2012

Language:

english

File:

PDF, 2.79 MB

english, 2012

20

Incidence, Clinical Predictors, Genomics, and Outcome of Acute Kidney Injury Among Trauma Patients

Bihorac, Azra, Delano, Matthew J., Schold, Jesse D., Lopez, Maria Cecilia, Nathens, Avery B., Maier, Ronald V., Layon, Abraham Joseph, Baker, Henry V., Moldawer, Lyle L.

Journal:

Annals of Surgery

Year:

2010

Language:

english

File:

PDF, 469 KB

english, 2010

21

Combination of Paclitaxel and Nitric Oxide as a Novel Treatment for the Reduction of Restenosis

Lin, Chia-En, Garvey, David S., Janero, David R., Letts, L. Gordon, Marek, Przemyslaw, Richardson, Stewart K., Serebryanik, Diana, Shumway, Matthew J., Tam, S. William, Trocha, A. Mark, Young, Delano

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 120 KB

english, 2004

22

The Interactive Effect of Traumatic Brain Injury and Psychiatric Symptoms on Cognition Among Late Middle-Aged Men: Findings from the Vietnam Era Twin Study of Aging (VETSA)

Kaup, Allison, Toomey, Rosemary, Bangen, Katherine J, Delano-Wood, Lisa, Yaffe, Kristine C., Panizzon, Matthew S, Lyons, Michael J, Franz, Carol E, Kremen, William S

Journal:

Journal of Neurotrauma

Year:

2018

Language:

english

File:

PDF, 498 KB

english, 2018

23

Cancer-induced Expansion and Activation of CD11b+Gr-1+ Cells Predispose Mice to Adenoviral-triggered Anaphylactoid-type Reactions

Pande, Kalyan, Ueda, Roanna, Machemer, Todd, Sathe, Manjiri, Tsai, Van, Brin, Elena, Delano, Matthew J, Van Rooijen, Nico, McClanahan, Terrill K, Talmadge, James E, Moldawer, Lyle L, Phillips, Joseph

Journal:

Molecular Therapy

Year:

2009

Language:

english

File:

PDF, 1.55 MB

english, 2009

24

Short-term versus long-term trauma mortality

Frydrych, Lynn M., Keeney-Bonthrone, Toby P., Gwinn, Elizabeth, Wakam, Glenn K., Anderson, Maia S., Delano, Matthew J.

Journal:

Journal of Trauma and Acute Care Surgery

Year:

2019

File:

PDF, 303 KB

2019

25

Pancreatic surgery

Duffy, John P., Delano, Matthew J., Reber, Howard A.

Journal:

Current Opinion in Gastroenterology

Year:

2002

Language:

english

File:

PDF, 294 KB

english, 2002

26

Trauma-induced heterotopic bone formation and the role of the immune system

Kraft, Casey T., Agarwal, Shailesh, Ranganathan, Kavitha, Wong, Victor W., Loder, Shawn, Li, John, Delano, Matthew J., Levi, Benjamin

Journal:

Journal of Trauma and Acute Care Surgery

Year:

2016

Language:

english

File:

PDF, 347 KB

english, 2016

27

CXCR3 blockade: a novel anti-sepsis approach?

Matthew J Delano, Lyle L Moldawer

Journal:

Critical Care (BioMed Central)

Year:

2012

Language:

english

File:

PDF, 82 KB

english, 2012

28

Diabetes and Sepsis: Risk, Recurrence, and Ruination

Frydrych, Lynn M., Fattahi, Fatemeh, He, Katherine, Ward, Peter A., Delano, Matthew J.

Journal:

Frontiers in Endocrinology

Year:

2017

Language:

english

File:

PDF, 1.22 MB

english, 2017

29

Braun enteroenterostomy is associated with reduced delayed gastric emptying and early resumption of oral feeding following pancreaticoduodenectomy

Steven N. Hochwald, Stephen R. Grobmyer, Alan W. Hemming, Eleanor Curran, David A. Bloom, Matthew Delano, Kevin E. Behrns, Edward M. Copeland, Stephen B. Vogel

Journal:

Journal of Surgical Oncology

Year:

2010

Language:

english

File:

PDF, 101 KB

english, 2010

30

Validation of the Modified Fatigue Impact Scale in Mild to Moderate Traumatic Brain Injury

Schiehser, Dawn M., Delano-Wood, Lisa, Jak, Amy J., Matthews, Scott C., Simmons, Alan N., Jacobson, Mark W., Filoteo, J. Vincent, Bondi, Mark W., Orff, Henry J., Liu, Lin

Journal:

Journal of Head Trauma Rehabilitation

Year:

2015

Language:

english

File:

PDF, 107 KB

english, 2015

31

Surgical Management of Clostridium difficile Infection: The Role of Colectomy

Delano, Matthew J., Cuschieri, Joseph

Journal:

Surgical Infections

Year:

2016

Language:

english

File:

PDF, 74 KB

english, 2016

32

Magic bullets and surrogate biomarkers circa 2009*

Delano, Matthew J., Moldawer, Lyle L.

Journal:

Critical Care Medicine

Year:

2009

Language:

english

File:

PDF, 1.17 MB

english, 2009

33

The Acute Immunological Response to Blood Transfusion Is Influenced by Polymicrobial Sepsis

Nacionales, Dina C., Cuenca, Alex G., Ungaro, Ricardo, Gentile, Lori F., Joiner, Dallas, Satoh, Minoru, Lomas-Neira, Joanne, Ayala, Alfred, Bihorac, Azra, Delano, Matthew J., Ang, Darwin N., Efron, Ph

Journal:

Year:

2012

Language:

english

File:

PDF, 4.13 MB

english, 2012

34

Role of complement C5a and histones in septic cardiomyopathy

Fattahi, Fatemeh, Frydrych, Lynn M., Bian, Guowu, Kalbitz, Miriam, Herron, Todd J., Malan, Elizabeth A., Delano, Matthew J., Ward, Peter A.

Journal:

Molecular Immunology

Year:

2018

Language:

english

File:

PDF, 1.52 MB

english, 2018

35

Prehospital Resuscitation of Traumatic Hemorrhagic Shock with Hypertonic Solutions Worsens Hypocoagulation and Hyperfibrinolysis

Delano, Matthew J., Rizoli, Sandro B., Rhind, Shawn G., Cuschieri, Joseph, Junger, Wolfgang, Baker, Andrew J., Dubick, Michael A., Hoyt, David B., Bulger, Eileen M.

Journal:

Year:

2015

Language:

english

File:

PDF, 2.73 MB

english, 2015

36

Pre-Diabetes is Associated with Increased Sepsis Mortality

Keeney-Bonthrone, Toby P., Frydrych, Lynn M., Jewell, Elizabeth S., Engoren, Milo C., Delano, Matthew J.

Journal:

Journal of the American College of Surgeons

Year:

2019

File:

PDF, 86 KB

2019

37

GM-CSF Administration Improves Defects in Innate Immunity and Sepsis Survival in Obese Diabetic Mice

Frydrych, Lynn M., Bian, Guowu, Fattahi, Fatemeh, Morris, Susan B., O’Rourke, Robert W., Lumeng, Carey N., Kunkel, Steven L., Ward, Peter A., Delano, Matthew J.

Journal:

The Journal of Immunology

Year:

2018

Language:

english

File:

PDF, 2.37 MB

english, 2018

38

Toward understanding of differences in current cloud retrievals of ARM ground-based measurements

Zhao, Chuanfeng, Xie, Shaocheng, Klein, Stephen A., Protat, Alain, Shupe, Matthew D., McFarlane, Sally A., Comstock, Jennifer M., Delanoë, Julien, Deng, Min, Dunn, Maureen, Hogan, Robin J., Huang, Don

Journal:

Journal of Geophysical Research

Year:

2012

Language:

english

File:

PDF, 2.96 MB

english, 2012

39

In situ assembly of enzyme inhibitors using extended tethering

Erlanson, Daniel A., Lam, Joni W., Wiesmann, Christian, Luong, Tinh N., Simmons, Robert L., DeLano, Warren L., Choong, Ingrid C., Burdett, Matthew T., Flanagan, W. Michael, Lee, Dennis

Journal:

Nature Biotechnology

Year:

2003

Language:

english

File:

PDF, 1.22 MB

english, 2003

40

Corrigendum to “A comparison of the cyclooxygenase inhibitor-NO donors (CINOD), NMI-1182 and AZD3582, using in vitro biochemical and pharmacological methods” [Biochem. Pharmacol. 70/9 (2005) 1343–1351]

Delano V. Young, Edward D. Cochran, Vijay Dhawan, Richard A. Earl, James L. Ellis, David S. Garvey, David R. Janero, Subhash P. Khanapure, L. Gordon Letts, Terry L. Melim, Madhavi G. Murty, Matthew J.

Journal:

Biochemical Pharmacology

Year:

2006

Language:

english

File:

PDF, 83 KB

english, 2006

41

Laparoscopic Esophagomyotomy for Achalasia

Dempsey, Daniel T., Delano, Matthew, Bradley, Kevin, Kolff, Jeffrey, Fisher, Carol, Caroline, Dina, Gaughan, John, Meilahn, John E, Daly, John M.

Journal:

Annals of Surgery

Year:

2004

Language:

english

File:

PDF, 1.08 MB

english, 2004

42

Whatʼs New in Shock, August 2019?

Machado-Aranda, David, Delano, Matthew J., Raghavendran, Krishnan

Journal:

Year:

2019

File:

PDF, 127 KB

2019

43

SEX, OBESITY AND TYPE 2 DIABETES AFFECT THE INTRAMYOCELLULAR FATE OF GLUCOSE IN HUMANS

Linda Ruth Peterson, Pilar Herrero, C. Huie Lin, Matthew Lyons, Carmen Dence, Zulfia Kisrieva-Ware, Alan D. Waggoner, Victor G. Davila-Roman, Deborah Delano, Robert J. Gropler

Journal:

Journal of the American College of Cardiology

Year:

2011

Language:

english

File:

PDF, 280 KB

english, 2011

44

Obesity and type 2 diabetes mellitus drive immune dysfunction, infection development, and sepsis mortality

Frydrych, Lynn M., Bian, Guowu, O'Lone, David E., Ward, Peter A., Delano, Matthew J.

Journal:

Journal of Leukocyte Biology

Year:

2018

Language:

english

File:

PDF, 311 KB

english, 2018

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